2024-03-29T05:33:29Z
https://teapot.lib.ocha.ac.jp/oai
oai:teapot.lib.ocha.ac.jp:00004850
2022-12-12T06:03:24Z
226:216:221
Favorable Effects of Tea on Reducing the Cognitive Deficits and Brain Morphological Changes in Senescence-Accelerated Mice
CHAN, Yin-Ching
HOSODA, Kazuaki
TSAI, Chin-Ju
YAMAMOTO, Shigeru
WANG, Ming-Fu
open access
日本ビタミン学会
本文データは学協会の許諾に基づきCiNiiから複製したものである
490
医学
oolong tea
green tea
learning and memory
brain degeneration
application/pdf
学術雑誌論文
The present study was carried out to explore the effects of oolong and green teas on improving the memory deficits and brain pathological changes in senescence accelerated-prone mice P8 (SAMP8). Six-month-old mice were supplied with oolong tea, green tea or water as the sole drinking fluid for 16wk. The memory ability of mice was evaluated by passive and active avoidance tests, while the extent of the brain degeneration was measured by the spongiosis grades and the lipofuscin percentage in the hippocampus. The total grading score and serum biochemical levels were also measured. The results indicated that the mice supplemented with the oolong and green tea drinks reversed the cognitive impairment, lessened the spongy degeneration and lipofuscin, and increased the serum Trolox equivalent antioxidant capacity more than the control group. The total grading score of the oolong tea group was lower than that of the control group in male mice, whereas it did not differ among female groups. No differentiations in the concentrations of total cholesterol, triglyceride, glucose, iron or hemoglobin were observed among three d\<br/>rink groups. In conclusion, oolong and green teas could reduce the deteriorations of cognitive ability, brain degenerative changes and aging process in SAMP8, probably through the potent antioxidative activity of the tea.
日本ビタミン学会
2006-08
eng
journal article
VoR
http://hdl.handle.net/10083/33572
https://teapot.lib.ocha.ac.jp/records/4850
http://ci.nii.ac.jp/naid/110004789055
AA00703822
03014800
Journal of nutritional science and vitaminology
52
4
266
273
https://teapot.lib.ocha.ac.jp/record/4850/files/J of nutritional science and vitaminology52(4)_yamamoto.pdf
application/pdf
1.6 MB
2018-04-23