@article{oai:teapot.lib.ocha.ac.jp:00034800, author = {Kitagaki, Haruko and Matsumoto, Isamu and Seno, Nobuko and Nagase, Sumi}, issue = {2}, journal = {お茶の水女子大學自然科學報告}, month = {Dec}, note = {application/pdf, 紀要論文, The cell surface glycoconjugates of various rat ascites hepatoma cell lines with different degrees of adhesiveness were compared, by binding assays, using ^<125>I-labelled lectins. Effects of neuraminidase, TPCK-trypsin and chondroitinase ABC treatment of the cells, on the number of lectin receptor sites were also studied. The TPCK-trypsin treatment caused a marked decrease in the number of peanut agglutinin receptor sites on the island forming and mixed cell types. The decrease of wheat germ agglutinin receptor sites and the increase of castor bean agglutinin receptor sites, after neuraminidase treatment, were larger on the free cell type. It is therefore possible that α-sialyl-β-D-galactosyl residues are abundant on the cell surface of this type, and that its low cell adhesiveness may be due to a electrostatic repulsion of negative charges of the sialic acid.}, pages = {115--126}, title = {Difference of Lectin Receptors Between the Free Cell Type and Island Forming Cell Type of Rat Ascites Hepatoma Cells}, volume = {32}, year = {1981} }