{"created":"2021-03-01T06:06:40.542829+00:00","id":4854,"links":{},"metadata":{"_buckets":{"deposit":"ee6473cc-28d5-4d11-8a48-d01d8bedaaf1"},"_deposit":{"id":"4854","owners":[],"pid":{"revision_id":0,"type":"depid","value":"4854"},"status":"published"},"_oai":{"id":"oai:teapot.lib.ocha.ac.jp:00004854","sets":["226:216:221"]},"control_number":"4854","item_12_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"282","bibliographicPageStart":"277","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"Journal of nutritional science and vitaminology"}]}]},"item_12_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_12_description_46":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"学術雑誌論文","subitem_description_type":"Other"}]},"item_12_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Endogenous natriuretic factors are believed to be responsible for extracellular fluid homeostasis in mammals. A new endogenous natriuretic factor, Loma Linda University-alpha (LLU-α) has recently been proven to be a 2,7,8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman (γ-CEHC), which is a metabolite of γ-tocopherol (γ-Toc). The purpose of this study was to investigate whether γ-Toc could accelerate sodium excretion into rat urine as a natriuretic hormone precursor. Male SD strain rats were divided into two groups ; one was a control diet group, while the other was a high NaCl group (50 g/kg diet). Next, the two groups were each subdivided into two groups consisting of a placebo group and a γ-Toc group. After the oral administration of one experimental dose of 20 mg γ-Toc or placebo, rat urine was collected at 6 h intervals for 24 h, and then the urine volume, sodium and potassium and γ-CEHC content were determined. γ-Toc increased in the urine volume of the high-NaCl intake group. The sodium excretion in the high-NaCl group given γ-Toc was 8.29±2.20 g, while in the control group given γ-Toc it was 6.24±1.49 g from 12-18 h. In contrast, the potassium excretion in the rat urine did not change in any of the groups. Our findings suggested that γ-Toc accelerates the degree of sodium excretion in rats with a high sodium intake.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_12_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本ビタミン学会"}]},"item_12_relation_54":{"attribute_name":"異版である","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ci.nii.ac.jp/naid/110002703999","subitem_relation_type_select":"URI"}}]},"item_12_rights_14":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"日本ビタミン学会"},{"subitem_rights":"本文データは学協会の許諾に基づきCiNiiから複製したものである"}]},"item_12_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_12_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00703822","subitem_source_identifier_type":"NCID"}]},"item_12_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03014800","subitem_source_identifier_type":"ISSN"}]},"item_12_subject_20":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_12_subject_24":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"医学","subitem_subject_scheme":"Other"}]},"item_12_text_18":{"attribute_name":"形態","attribute_value_mlt":[{"subitem_text_value":"615605 bytes"}]},"item_12_text_47":{"attribute_name":"資源タイプ・ローカル","attribute_value_mlt":[{"subitem_text_value":"学術雑誌論文"}]},"item_12_text_48":{"attribute_name":"資源タイプ・NII","attribute_value_mlt":[{"subitem_text_value":"Journal Article"}]},"item_12_text_49":{"attribute_name":"資源タイプ・DCMI","attribute_value_mlt":[{"subitem_text_value":"text"}]},"item_12_text_50":{"attribute_name":"資源タイプ・ローカル表示コード","attribute_value_mlt":[{"subitem_text_value":"01"}]},"item_12_text_79":{"attribute_name":"所属","attribute_value_mlt":[{"subitem_text_value":"Institute of Environmental Science for Human Life, Ochanomizu University"},{"subitem_text_value":"Institute of Environmental Science for Human Life, Ochanomizu University"},{"subitem_text_value":"Institute of Environmental Science for Human Life, Ochanomizu University"},{"subitem_text_value":"Yamano Beauty College"},{"subitem_text_value":"Eisai Co., Ltd."},{"subitem_text_value":"Ibaraki Christian University"},{"subitem_text_value":"Institute of Environmental Science for Human Life, Ochanomizu University"}]},"item_1622774516477":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"UTO, Harumi"}],"nameIdentifiers":[{"nameIdentifier":"88943","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KIYOSE, Chikako"}],"nameIdentifiers":[{"nameIdentifier":"88944","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SAITO, Hisako"}],"nameIdentifiers":[{"nameIdentifier":"88945","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"UEDA, Tadahiko"}],"nameIdentifiers":[{"nameIdentifier":"88946","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"NAKAMURA, Takaharu"}],"nameIdentifiers":[{"nameIdentifier":"88947","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"IGARASHI, Osamu"}],"nameIdentifiers":[{"nameIdentifier":"88948","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KONDO, Kazuo"}],"nameIdentifiers":[{"nameIdentifier":"88949","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-04-23"}],"displaytype":"detail","filename":"J of nutritional science and vitaminology50(4)_utokiyosesaitokondo.pdf","filesize":[{"value":"615.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"J of nutritional science and vitaminology50(4)_utokiyosesaitokondo.pdf","url":"https://teapot.lib.ocha.ac.jp/record/4854/files/J of nutritional science and vitaminology50(4)_utokiyosesaitokondo.pdf"},"version_id":"e20485dd-848d-4731-9101-bef61fd9cee4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"γ-tocopherol","subitem_subject_scheme":"Other"},{"subitem_subject":"γ-CEHC","subitem_subject_scheme":"Other"},{"subitem_subject":"natriuretic hormone","subitem_subject_scheme":"Other"},{"subitem_subject":"sodium excretion","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"γ-Tocopherol Enhances Sodium Excretion as a Natriuretic Hormone Precursor","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"γ-Tocopherol Enhances Sodium Excretion as a Natriuretic Hormone Precursor","subitem_title_language":"en"}]},"item_type_id":"12","owner":"17","path":["221"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2009-04-27"},"publish_date":"2009-04-27","publish_status":"0","recid":"4854","relation_version_is_last":true,"title":["γ-Tocopherol Enhances Sodium Excretion as a Natriuretic Hormone Precursor"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2022-12-12T05:29:20.145390+00:00"}