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In normal cells, no telomerase activity was detected, but after transformation of these cells with SV40 or ^\u003c60\u003eCo, cells changed into immortal and an apparent telomerase activity expressed. Telomere length of these cells were determined and a distinct shortening of telomeres was observed in one case of transformants,and in other cases, telomere elongation was observed. DNA polymerase α activity was also determined, and high activity was detected in the cells having long telomeres, but low activity was detected in the cells bearing short telomeres. The expression of telomerase may be required as a critical step for tumorgenesis, but telomere length may not be a determinants of malignancy of tumor cells.", "subitem_description_type": "Other"}]}, "item_11_full_name_2": {"attribute_name": "著者(ヨミ)", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "70621", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "ナカノ, マリコ"}]}, {"nameIdentifiers": [{"nameIdentifier": "70622", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "シマダ, ユキコ"}]}, {"nameIdentifiers": [{"nameIdentifier": "70623", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "コバヤシ, テツユキ"}]}, {"nameIdentifiers": [{"nameIdentifier": "70624", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "ムラカミ-ムロフシ, キミコ"}]}]}, "item_11_publisher_36": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "お茶の水女子大学"}]}, "item_11_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00033958", "subitem_source_identifier_type": "NCID"}]}, "item_11_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00298190", "subitem_source_identifier_type": "ISSN"}]}, "item_11_subject_20": {"attribute_name": "日本十進分類法", "attribute_value_mlt": [{"subitem_subject": "400", "subitem_subject_scheme": "NDC"}]}, "item_11_text_18": {"attribute_name": "形態", "attribute_value_mlt": [{"subitem_text_value": "671156 bytes"}]}, "item_11_text_47": {"attribute_name": "資源タイプ・ローカル", "attribute_value_mlt": [{"subitem_text_value": "紀要論文"}]}, "item_11_text_48": {"attribute_name": "資源タイプ・NII", "attribute_value_mlt": [{"subitem_text_value": "Departmental Bulletin Paper"}]}, "item_11_text_49": {"attribute_name": "資源タイプ・DCMI", "attribute_value_mlt": [{"subitem_text_value": "text"}]}, "item_11_text_50": {"attribute_name": "資源タイプ・ローカル表示コード", "attribute_value_mlt": [{"subitem_text_value": "03"}]}, "item_11_text_79": {"attribute_name": "所属", "attribute_value_mlt": [{"subitem_text_value": "Department of Biology, Faculty of Science, Ochanomizu University"}, {"subitem_text_value": "Department of Biology, Faculty of Science, Ochanomizu University"}, {"subitem_text_value": "Department of Biology, Faculty of Science, Ochanomizu University"}, {"subitem_text_value": "Department of Biology, Faculty of Science, Ochanomizu University"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Nakano, Mariko"}], "nameIdentifiers": [{"nameIdentifier": "70617", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimada, Yukiko"}], "nameIdentifiers": [{"nameIdentifier": "70618", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kobayashi, Tetsuyuki"}], "nameIdentifiers": [{"nameIdentifier": "70619", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Murakami-Murofushi, Kimiko"}], "nameIdentifiers": [{"nameIdentifier": "70620", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-04-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00004470878.pdf", "filesize": [{"value": "671.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 671200.0, "url": {"label": "KJ00004470878.pdf", "url": "https://teapot.lib.ocha.ac.jp/record/34697/files/KJ00004470878.pdf"}, "version_id": "1e17aef2-69eb-4647-9bcb-0e274e9fdf80"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "EXPRESSION OF TELOMERASE ACTIVITY ASSOCIATED WITH TRANSFORMATION OF HUMAN FIBROBLASTS", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "EXPRESSION OF TELOMERASE ACTIVITY ASSOCIATED WITH TRANSFORMATION OF HUMAN FIBROBLASTS"}]}, "item_type_id": "11", "owner": "1", "path": ["667"], "permalink_uri": "http://hdl.handle.net/10083/851", "pubdate": {"attribute_name": "公開日", "attribute_value": "2007-04-23"}, "publish_date": "2007-04-23", "publish_status": "0", "recid": "34697", "relation": {}, "relation_version_is_last": true, "title": ["EXPRESSION OF TELOMERASE ACTIVITY ASSOCIATED WITH TRANSFORMATION OF HUMAN FIBROBLASTS"], "weko_shared_id": null}