WEKO3
アイテム
EXPRESSION OF TELOMERASE ACTIVITY ASSOCIATED WITH TRANSFORMATION OF HUMAN FIBROBLASTS
http://hdl.handle.net/10083/851
http://hdl.handle.net/10083/85133dd82f4-b677-47ca-bcf8-5b308c87e959
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00004470878.pdf (671.2 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-04-23 | |||||
| タイトル | ||||||
| タイトル | EXPRESSION OF TELOMERASE ACTIVITY ASSOCIATED WITH TRANSFORMATION OF HUMAN FIBROBLASTS | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 著者 |
Nakano, Mariko
× Nakano, Mariko× Shimada, Yukiko× Kobayashi, Tetsuyuki× Murakami-Murofushi, Kimiko |
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| 著者(ヨミ) | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 70621 | |||||
| 姓名 | ナカノ, マリコ | |||||
| 著者(ヨミ) | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 70622 | |||||
| 姓名 | シマダ, ユキコ | |||||
| 著者(ヨミ) | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 70623 | |||||
| 姓名 | コバヤシ, テツユキ | |||||
| 著者(ヨミ) | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 70624 | |||||
| 姓名 | ムラカミ-ムロフシ, キミコ | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Telomerase activity and telomere length in normal and immortalized human fibroblasts were determined. In normal cells, no telomerase activity was detected, but after transformation of these cells with SV40 or ^<60>Co, cells changed into immortal and an apparent telomerase activity expressed. Telomere length of these cells were determined and a distinct shortening of telomeres was observed in one case of transformants,and in other cases, telomere elongation was observed. DNA polymerase α activity was also determined, and high activity was detected in the cells having long telomeres, but low activity was detected in the cells bearing short telomeres. The expression of telomerase may be required as a critical step for tumorgenesis, but telomere length may not be a determinants of malignancy of tumor cells. | |||||
| 書誌情報 |
お茶の水女子大學自然科學報告 巻 48, 号 2, p. 39-44, 発行日 1998-03-12 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00298190 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00033958 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 形態 | ||||||
| 671156 bytes | ||||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 400 | |||||
| 出版者 | ||||||
| 出版者 | お茶の水女子大学 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 紀要論文 | |||||
| 資源タイプ・ローカル | ||||||
| 紀要論文 | ||||||
| 資源タイプ・NII | ||||||
| Departmental Bulletin Paper | ||||||
| 資源タイプ・DCMI | ||||||
| text | ||||||
| 資源タイプ・ローカル表示コード | ||||||
| 03 | ||||||
| 所属 | ||||||
| Department of Biology, Faculty of Science, Ochanomizu University | ||||||
| 所属 | ||||||
| Department of Biology, Faculty of Science, Ochanomizu University | ||||||
| 所属 | ||||||
| Department of Biology, Faculty of Science, Ochanomizu University | ||||||
| 所属 | ||||||
| Department of Biology, Faculty of Science, Ochanomizu University | ||||||
