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  1. 紀要
  2. お茶の水女子大學自然科學報告
  3. 48(2)

EXPRESSION OF TELOMERASE ACTIVITY ASSOCIATED WITH TRANSFORMATION OF HUMAN FIBROBLASTS

http://hdl.handle.net/10083/851
http://hdl.handle.net/10083/851
33dd82f4-b677-47ca-bcf8-5b308c87e959
名前 / ファイル ライセンス アクション
KJ00004470878.pdf KJ00004470878.pdf (671.2 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2007-04-23
タイトル
タイトル EXPRESSION OF TELOMERASE ACTIVITY ASSOCIATED WITH TRANSFORMATION OF HUMAN FIBROBLASTS
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Nakano, Mariko

× Nakano, Mariko

WEKO 70617

Nakano, Mariko

Search repository
Shimada, Yukiko

× Shimada, Yukiko

WEKO 70618

Shimada, Yukiko

Search repository
Kobayashi, Tetsuyuki

× Kobayashi, Tetsuyuki

WEKO 70619

Kobayashi, Tetsuyuki

Search repository
Murakami-Murofushi, Kimiko

× Murakami-Murofushi, Kimiko

WEKO 70620

Murakami-Murofushi, Kimiko

Search repository
著者(ヨミ)
識別子 70621
識別子Scheme WEKO
姓名 ナカノ, マリコ
著者(ヨミ)
識別子 70622
識別子Scheme WEKO
姓名 シマダ, ユキコ
著者(ヨミ)
識別子 70623
識別子Scheme WEKO
姓名 コバヤシ, テツユキ
著者(ヨミ)
識別子 70624
識別子Scheme WEKO
姓名 ムラカミ-ムロフシ, キミコ
内容記述
内容記述タイプ Other
内容記述 Telomerase activity and telomere length in normal and immortalized human fibroblasts were determined. In normal cells, no telomerase activity was detected, but after transformation of these cells with SV40 or ^<60>Co, cells changed into immortal and an apparent telomerase activity expressed. Telomere length of these cells were determined and a distinct shortening of telomeres was observed in one case of transformants,and in other cases, telomere elongation was observed. DNA polymerase α activity was also determined, and high activity was detected in the cells having long telomeres, but low activity was detected in the cells bearing short telomeres. The expression of telomerase may be required as a critical step for tumorgenesis, but telomere length may not be a determinants of malignancy of tumor cells.
書誌情報 お茶の水女子大學自然科學報告

巻 48, 号 2, p. 39-44, 発行日 1998-03-12
ISSN
収録物識別子タイプ ISSN
収録物識別子 00298190
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00033958
フォーマット
内容記述タイプ Other
内容記述 application/pdf
形態
671156 bytes
日本十進分類法
主題Scheme NDC
主題 400
出版者
出版者 お茶の水女子大学
資源タイプ
内容記述タイプ Other
内容記述 紀要論文
資源タイプ・ローカル
紀要論文
資源タイプ・NII
Departmental Bulletin Paper
資源タイプ・DCMI
text
資源タイプ・ローカル表示コード
03
所属
Department of Biology, Faculty of Science, Ochanomizu University
所属
Department of Biology, Faculty of Science, Ochanomizu University
所属
Department of Biology, Faculty of Science, Ochanomizu University
所属
Department of Biology, Faculty of Science, Ochanomizu University
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