WEKO3
アイテム
Extracellular Polysaccharide from a True Slime Mold, Physarum Polycephalum. Polymerization and Auto-Degradation Associated with Cell Growth, and Its Inhibitory Activity on Eukaryotic DNA Polymerase α
http://hdl.handle.net/10083/813
http://hdl.handle.net/10083/813142a377f-4952-468a-8d0c-ca4f0bca04d9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00004470767.pdf (485.2 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-04-23 | |||||
| タイトル | ||||||
| タイトル | Extracellular Polysaccharide from a True Slime Mold, Physarum Polycephalum. Polymerization and Auto-Degradation Associated with Cell Growth, and Its Inhibitory Activity on Eukaryotic DNA Polymerase α | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Shimada, Yukiko
× Shimada, Yukiko× Murakami-Murofushi, Kimiko× Shioda, Masaki× Ohta, Jiro |
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| 作成者(ヨミ) | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 70459 | |||||
| 姓名 | シマダ, ユキコ | |||||
| 作成者(ヨミ) | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 70460 | |||||
| 姓名 | ムラカミ-ムロフシ, キミコ | |||||
| 作成者(ヨミ) | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 70461 | |||||
| 姓名 | シオダ, マサキ | |||||
| 作成者(ヨミ) | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 70462 | |||||
| 姓名 | オオタ, ジロウ | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Plasmodia of a true slime mold, Physarum polycephalum, synthesize slime polysaccharide and secrete it outside the organisms. This substance was shown to be synthesized and polymerized with cell growth. And when the cells reached a plateau of growth in a nutrient medium, degradation of the polysaccharide and autolysis of the cells occurred. The composition of polysaccharides from different strains of Physarum, F/J or Lu strains, were almost the same, but polymerization rates of them were different. We purified the polysaccharides from these two strains and characterized them. Both of them mainly consisted of galactose (Gal) residue having phosphate (-PO_4) and sulfate (-SO_4) moieties, and the molar ratios of these constituents were 9:1:1 for F/J and 9:2:1 for Lu, respectively. The biological effect of slime polysacchapide was examined and we found that it had a specific inhibitory activity on eukaryotic DNA polymerase α, and degree of inhibition was not dependent on the length of the polysaccharide. | |||||
| 書誌情報 |
お茶の水女子大學自然科學報告 巻 42, 号 2, p. 39-47, 発行日 1991-12-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00298190 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00033958 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 形態 | ||||||
| 値 | 485185 bytes | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 400 | |||||
| 出版者 | ||||||
| 出版者 | お茶の水女子大学 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 紀要論文 | |||||
| 資源タイプ・ローカル | ||||||
| 値 | 紀要論文 | |||||
| 資源タイプ・NII | ||||||
| 値 | Departmental Bulletin Paper | |||||
| 資源タイプ・DCMI | ||||||
| 値 | text | |||||
| 資源タイプ・ローカル表示コード | ||||||
| 値 | 03 | |||||
| 所属 | ||||||
| 値 | Department of Biology, Faculty of Science, Ochanomizu University | |||||
| 所属 | ||||||
| 値 | Department of Biology, Faculty of Science, Ochanomizu University | |||||
| 所属 | ||||||
| 値 | Department of Physiological Chemistry and Nutrition, Faculty of Medicine, University of Tokyo | |||||
| 所属 | ||||||
| 値 | Department of Biology, Faculty of Science, Ochanomizu University | |||||
