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Difference in Plasma Metabolite Concentration after Ingestion of Lemon Flavonoids and Their Aglycones in Humans
http://hdl.handle.net/10083/33579
http://hdl.handle.net/10083/335797831c9c5-8dc2-4cad-849c-ec7fff1b84fa
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
J of nutritional science and vitaminology52(1)_sakuraikondo.pdf (735.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2009-04-30 | |||||
| タイトル | ||||||
| タイトル | Difference in Plasma Metabolite Concentration after Ingestion of Lemon Flavonoids and Their Aglycones in Humans | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | lemon flavonoid | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | eriocitrin | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | plasma | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | human | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | ingestion | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 著者 |
MIYAKE, Yoshiaki
× MIYAKE, Yoshiaki× SAKURAI, Chika× USUDA, Mika× FUKUMOTO, Syuichi× HIRAMITSU, Masanori× SAKAIDA, Kazuhiro× OSAWA, Toshihiko× KONDO, Kazuo |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The concentrations of metabolites in human plasma after ingestion of flavanone glycosides (FG) and their aglycones (FA) in lemon were examined. FG consisting abundantly of eriocitrin were prepared from lemon peel and FA consisting abundantly of eriodictyol were prepared from FG by treatment with β-glucosidase. Eriodictyol, homoeriodictyol, and hesperetin in plasma up to 4 h after ingestion of FG with water or FA with water by subjects were not detected in plasma of non-enzyme treatment but in plasma after treatment with β-glucronidase and sulfatase. Metabolites in plasma after ingestion of FG and FA in humans were shown to exist as the glucuro- and/or sulfo-conjugates of eriodictyol, homoeriodictyol, and hesperetin. After ingestion of FA, the concentration of metabolites in plasma exhibited a high maximum peak at 1 h. The AUC (area under the blood concentration time curve) level of metabolites of FA was higher than that of FG. FA were suggested to be absorbed faster and in higher amounts than FG. The AUC of metabolites in subject plasma after ingestion of FG with flavonoid-depleted lemon juice was shown to change\<br/> to a low level in comparison with that of FG with water. The maximum concentration peak of metabolites in plasma was faster at 0.5 h than FA with water but the AUC level was similar to FA with water, when subjects ingested FA with vodka (40% ethanol). The absorption hour of FG and FA was shown to be affected by the co-existing solution. | |||||
| 書誌情報 |
Journal of nutritional science and vitaminology 巻 52, 号 1, p. 54-60, 発行日 2006-02 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 03014800 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00703822 | |||||
| 権利 | ||||||
| 権利情報 | 日本ビタミン学会 | |||||
| 権利 | ||||||
| 権利情報 | 本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 形態 | ||||||
| 値 | 735685 bytes | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 490 | |||||
| NIIサブジェクト | ||||||
| 主題Scheme | Other | |||||
| 主題 | 医学 | |||||
| 出版者 | ||||||
| 出版者 | 日本ビタミン学会 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 学術雑誌論文 | |||||
| 資源タイプ・ローカル | ||||||
| 値 | 学術雑誌論文 | |||||
| 資源タイプ・NII | ||||||
| 値 | Journal Article | |||||
| 資源タイプ・DCMI | ||||||
| 値 | text | |||||
| 資源タイプ・ローカル表示コード | ||||||
| 値 | 01 | |||||
| 異版である | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://ci.nii.ac.jp/naid/110004656460 | |||||
| 所属 | ||||||
| 値 | Faculty of Human Wellness, Tokaigakuen University | |||||
| 所属 | ||||||
| 値 | Institute of Environmental Science for Human Life, Ochanomizu University | |||||
| 所属 | ||||||
| 値 | Institute of Environmental Science for Human Life, Ochanomizu University | |||||
| 所属 | ||||||
| 値 | Pokka Corporation Ltd. | |||||
| 所属 | ||||||
| 値 | Pokka Corporation Ltd. | |||||
| 所属 | ||||||
| 値 | Pokka Corporation Ltd. | |||||
| 所属 | ||||||
| 値 | Laboratory of Food and Biodynamics Graduate School of Bioagricultural Sciences, Nagoya University | |||||
| 所属 | ||||||
| 値 | Institute of Environmental Science for Human Life, Ochanomizu University | |||||
