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γ-Tocopherol Enhances Sodium Excretion as a Natriuretic Hormone Precursor
http://hdl.handle.net/10083/33571
http://hdl.handle.net/10083/335719b90fd92-018e-49a6-b0a2-7c7cdd5f389a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
J of nutritional science and vitaminology50(4)_utokiyosesaitokondo.pdf (615.6 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2009-04-27 | |||||
| タイトル | ||||||
| タイトル | γ-Tocopherol Enhances Sodium Excretion as a Natriuretic Hormone Precursor | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | γ-tocopherol | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | γ-CEHC | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | natriuretic hormone | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | sodium excretion | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 著者 |
UTO, Harumi
× UTO, Harumi× KIYOSE, Chikako× SAITO, Hisako× UEDA, Tadahiko× NAKAMURA, Takaharu× IGARASHI, Osamu× KONDO, Kazuo |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Endogenous natriuretic factors are believed to be responsible for extracellular fluid homeostasis in mammals. A new endogenous natriuretic factor, Loma Linda University-alpha (LLU-α) has recently been proven to be a 2,7,8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman (γ-CEHC), which is a metabolite of γ-tocopherol (γ-Toc). The purpose of this study was to investigate whether γ-Toc could accelerate sodium excretion into rat urine as a natriuretic hormone precursor. Male SD strain rats were divided into two groups ; one was a control diet group, while the other was a high NaCl group (50 g/kg diet). Next, the two groups were each subdivided into two groups consisting of a placebo group and a γ-Toc group. After the oral administration of one experimental dose of 20 mg γ-Toc or placebo, rat urine was collected at 6 h intervals for 24 h, and then the urine volume, sodium and potassium and γ-CEHC content were determined. γ-Toc increased in the urine volume of the high-NaCl intake group. The sodium excretion in the high-NaCl group given γ-Toc was 8.29±2.20 g, while in the control group given γ-Toc it was 6.24±1.49 g from 12-18 h. In contrast, the potassium excretion in the rat urine did not change in any of the groups. Our findings suggested that γ-Toc accelerates the degree of sodium excretion in rats with a high sodium intake. | |||||
| 言語 | en | |||||
| 書誌情報 |
Journal of nutritional science and vitaminology 巻 50, 号 4, p. 277-282, 発行日 2004-08 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 03014800 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00703822 | |||||
| 権利 | ||||||
| 権利情報 | 日本ビタミン学会 | |||||
| 権利 | ||||||
| 権利情報 | 本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 形態 | ||||||
| 615605 bytes | ||||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 490 | |||||
| NIIサブジェクト | ||||||
| 主題Scheme | Other | |||||
| 主題 | 医学 | |||||
| 出版者 | ||||||
| 出版者 | 日本ビタミン学会 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 学術雑誌論文 | |||||
| 資源タイプ・ローカル | ||||||
| 学術雑誌論文 | ||||||
| 資源タイプ・NII | ||||||
| Journal Article | ||||||
| 資源タイプ・DCMI | ||||||
| text | ||||||
| 資源タイプ・ローカル表示コード | ||||||
| 01 | ||||||
| 異版である | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://ci.nii.ac.jp/naid/110002703999 | |||||
| 所属 | ||||||
| Institute of Environmental Science for Human Life, Ochanomizu University | ||||||
| 所属 | ||||||
| Institute of Environmental Science for Human Life, Ochanomizu University | ||||||
| 所属 | ||||||
| Institute of Environmental Science for Human Life, Ochanomizu University | ||||||
| 所属 | ||||||
| Yamano Beauty College | ||||||
| 所属 | ||||||
| Eisai Co., Ltd. | ||||||
| 所属 | ||||||
| Ibaraki Christian University | ||||||
| 所属 | ||||||
| Institute of Environmental Science for Human Life, Ochanomizu University | ||||||
